Type: Full-Time
Posted: 05/06/2023
Category: Physicians; +1
Med-Microbiology and Molecular Genetics – Pennsylvania-Pittsburgh – (23002742)
The Laboratory of Dr. Shou-Jiang (SJ) Gao in the Cancer Virology Program (CVP) at UPMC Hillman Cancer Center is recruiting newly graduated, innovative, highly independent, and motivated candidates with molecular and cellular biology backgrounds to fill in numerous Postdoctoral Positions. Gao’s lab primarily studies oncogenic Kaposi’s sarcoma-associated herpesvirus (KSHV) and its associated cancers. The lab has developed numerous infection models and used them to study the mechanisms of KSHV infection, replication, the establishment of latency, and induction of cancer. These works lead to the delineations of KSHV reprogramming of epigenome and epi transcriptome, rewiring of cellular metabolic pathways, evasion of innate immunity, and identification of novel therapeutic targets and agents. The lab has enjoyed a long history of collaboration with computational biologists, particularly Dr. Yufei Huang, who is also in CVP, allowing the development of novel systems approaches for dissecting complex biological questions, including the recent development of novel analytic tools for spatially-resolved single-cell transcriptomics. Recent works have also identified novel tumor suppressive functions of an arginine sensor CASTOR1, which regulates both tumor and immune cells. Ongoing works are examining the functions of CASTOR1 in other types of cancer including lung cancer and HPV-associated head and neck squamous cell carcinoma, and innate and adaptive immunity in models of colitis and colon cancer.
The Hillman Cancer Center has a dynamic interactive environment and world-class investigators in cancer biology, virology, immunology, and genomics. The Gao lab is also affiliated with the Department of Microbiology and Molecular Genetics (MMG), which comprises 42 primary and 8 secondary faculty members with a focus on basic research in molecular biology, microbiology, virology, biochemistry, and developmental biology. In addition to driving independent research programs, investigators in the Hillman Cancer Center and MMG collaborate with scientists across all schools of the University of Pittsburgh and around the world on a wide range of fundamental and applied problems. The University has a broad range of basic and clinical research in microbiology, infectious diseases, and vaccinology. Other prominent entities in the Pitt microbiology community include the Center for Vaccine Research, Adult Infectious Diseases, Pediatric Infectious Diseases, Infectious Diseases & Microbiology in the School of Public Health and the Center for Medicine and the Microbiome. The University of Pittsburgh School of Medicine is enjoying unparalleled growth in its research, clinical, and academic missions. The University ranks 3rd among educational institutions in NIH funding according to preliminary NIH RePORTER data. The Postdoctoral Fellows will receive world-class training and have the opportunity to collaborate with diverse investigators.
Applicants should have an excellent track record with peer-reviewed publications, and possess a Ph.D., MD, or equivalent degree in a biomedical science or related field. Candidates with relevant experience are preferred. Please apply at Home | Talent Center: Careers at Pitt | University of Pittsburgh to requisition #23002742.
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Assignment Category Full-time regular
Campus Pittsburgh
Required Attachments Cover Letter, Curriculum Vitae
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